Cards Open Memorial Day Showdown With Brewers in Battle for 1st Place

May 25, 2026By Ray Mileur
Ray Mileur

The Cardinal Chronicle
Cardinals Open Memorial Day Showdown With Brewers in Battle for 1st Place
St. Louis, MO
By Ray Mileur

The St. Louis Cardinals did not get much baseball in over the weekend, but they will not need much help finding the stakes Monday afternoon in Milwaukee.

The Cardinals open a three-game Memorial Day series against the Milwaukee Brewers at American Family Field, with first pitch set for 1:10 p.m. CDT. Milwaukee enters the matinee at 30-20, holding first place in the National League Central and sitting 1½ games ahead of second-place St. Louis, which comes in at 29-22 after a weather-disrupted weekend in Cincinnati.

For the Cardinals, this is not just another holiday road game. It is an early measuring-stick series against the club currently setting the pace in the division. Memorial Day has long been one of baseball’s first checkpoints, and St. Louis arrives still very much in the hunt despite the uneven rhythm of the past few days.

Milwaukee, meanwhile, comes home trying to steady itself after dropping two of three to the Los Angeles Dodgers. The Brewers managed seven hits in Sunday’s 5-1 loss, but all seven were singles, and Milwaukee went 0-for-4 with runners in scoring position while grounding into two double plays.

Pitching Matchup
Cardinals: LHP Matthew Liberatore — 2-2, 4.70 ERA, 1.55 WHIP
Brewers: RHP Jacob Misiorowski — 4-2, 1.89 ERA, 0.88 WHIP

The opener presents a difficult assignment for the Cardinals’ offense. Jacob Misiorowski has been one of the hottest arms in the league, carrying a sub-2.00 ERA into the matchup and coming off a dominant stretch. In his last start, Misiorowski worked six shutout innings against the Cubs, allowing three hits with eight strikeouts and one walk. That outing extended his scoreless streak to 24⅓ consecutive innings over four starts.

Misiorowski’s combination of power stuff and improved command has helped anchor a Milwaukee pitching staff that has been one of the club’s biggest strengths. The Brewers enter the series with a team ERA around the mid-3.00s, and their ability to shorten games with quality starting pitching has helped them protect the top spot in the division.

For St. Louis, Matthew Liberatore gets the ball looking to stabilize his own line. His season numbers remain uneven, but there have been signs of swing-and-miss ability. In his most recent outing against Pittsburgh, Liberatore struck out nine but allowed four runs in 4⅔ innings, a start that summed up much of his season — enough stuff to compete, but not enough efficiency to work deep.

The key for Liberatore will be limiting traffic. His 1.55 WHIP leaves little margin for error against a Milwaukee lineup that can manufacture runs, put pressure on the defense, and turn walks or singles into crooked numbers. If he can keep the Brewers off the bases early, St. Louis has a chance to keep this one in reach and avoid asking too much of a bullpen that has had its rough patches.

Cardinals Outlook
The Cardinals arrive in Milwaukee with an offense capable of doing damage. St. Louis ranks among the better slugging clubs in the National League, and the middle of the order remains the club’s clearest path to taking control of games.

Jordan Walker continues to be the centerpiece of the Cardinals’ offensive surge, bringing impact power and a growing presence in the lineup. Against a pitcher like Misiorowski, the Cardinals may not get many mistakes, so the early at-bats matter. They need to avoid chasing velocity up, extend counts where possible, and force Milwaukee’s starter to work.

The rain-shortened weekend in Cincinnati complicates the rhythm, but it may also leave St. Louis with a fresher roster than expected. The Cardinals played only a limited weekend schedule after Sunday’s postponement, and that could matter as the club begins another important divisional road series.

Brewers Outlook
Milwaukee has been built around pitching, defense, and pressure. The Brewers are 16-11 at home, and American Family Field has not been an easy stop for visiting clubs.

The Brewers are also navigating their own roster and injury issues, particularly on the pitching side, with Brandon Woodruff and Quinn Priester among the notable arms listed as unavailable in recent reports. Even so, Milwaukee has continued to get frontline production from young arms such as Misiorowski and Kyle Harrison, keeping the Brewers at the top of the division.

Offensively, catcher William Contreras has been one of Milwaukee’s key bats, and the Brewers remain dangerous when they are getting runners on base ahead of their run producers. They did not do enough of that against the Dodgers on Sunday, but this is still a club that has won with balance rather than relying on one big-name thumper.

Old School Take
This is the kind of series that tells you something.

No, nobody wins the division on Memorial Day. But you can learn who handles the moment, who looks ready for the grind, and who still needs tightening up before summer gets serious.

For the Cardinals, the formula is plain enough: get a competitive start from Liberatore, keep Milwaukee from running wild on the bases, and make Misiorowski throw more than just comfortable power fastballs in the zone.

If St. Louis can turn this into a bullpen game by the middle innings, the Cardinals have a chance.

But if Misiorowski gets rolling early, it could be a long Memorial Day afternoon under the roof in Milwaukee.


The Cardinal Chronicle, in association with Gateway Sports